Asymmetric Synthesis of (+)-trans-Aerangis Lactone

Aejin Kim, Satyasheel Sharma, Jong Hwan Kwak, In Su Kim
2013 Bulletin of the Korean Chemical Society (Print)  
Asymmetric synthesis of (+)-trans-aerangis lactone was achieved from commercially available 1-hexanol or 1-hexanal in four steps via iridium-catalyzed diastereoselective and enantioselective carbonyl crotylation from the alcohol or aldehyde oxidation level, and ruthenium-catalyzed olefin metathesis.
doi:10.5012/bkcs.2013.34.1.75 fatcat:pdjqjgjgjff6hhbitizhqtyarm