Accurate measurement and estimation of glomerular filtration rate (GFR) is a key indicator for early diagnosis and accurate classification of chronic kidney diseases (CKD). Serum creatinine measurement is a common method for estimating GFR, however, its clinical use remains very limited. Recent studies demonstrate that cystatin C has been used extensively as a research tool for evaluation of renal function in CKD patients, and can more accurately predict all-cause mortality, cardiovascular

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... dity and mortality and the risk for end-stage renal disease. This article reviews the value of cystatin C in functional assessment and prognosis prediction in CKD patients. DOI: 10.11855/j.issn.0577-7402.2016.10.16