A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
In Vitro Activities of 13 Fluoroquinolones againstStaphylococcus aureus Isolates with Characterized Mutations in gyrA, gyrB, grlA, andnorA and against Wild-Type Isolates
1999
Antimicrobial Agents and Chemotherapy
Preserved Fulltext
The in vitro activities of 13 fluoroquinolones (FQs) were tested against 90 Staphylococcus aureus clinical isolates: 30 wild type for gyrA, gyrB, grlA andnorA and 60 with mutations in these genes. Clinafloxacin (CI-960), sparfloxacin, and grepafloxacin were the most active FQs against wild-type isolates (MICs at which 90% of isolates were inhibited, 0.06 to 0.1 μg/ml). Mutations in grlA did not affect the MICs of newer FQs. grlA-gyrA double mutations led to higher MICs for all the FQs tested.
doi:10.1128/aac.43.4.966
fatcat:zcj4smwownecphkfehc62zvf6q