Objective: To characterize the profile of compulsory notifications of exogenous intoxication in Foz do Iguaçu, Paraná, in the five-year period 2015 to 2019. Methods: Documentary, quantitative-analytical study of the sociodemographic and epidemiological profiles, of notifications of exogenous intoxication. The variables were collected in Individual Notification Forms of the Notifiable Diseases Information System (SINAN) with a sample of 2799 evaluated records. The data were tabulated in

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... ets, Microsoft Excel, and were analyzed using Sigma Plot, version 11.0. The results were expressed in absolute frequency and relative percentages. The analysis of associations between variables was performed using chi-square. Results: Regarding the socio-demographic and economic profile, it was found that the average age of victims of poisoning is higher for the male population, 33 years old (± 15.48), with a preponderance of intoxications among white, female individuals (n = 1174; 41.94%) and male (n = 736; 26.30%), with complete secondary education for women (n = 318; 11.36%) and incomplete primary education for men (n = 227; 8.11%), residing in urban areas, female (n = 1594; 56.95%) and male (n = 1069; 38.19%), whose occupation is in formal work, female (n = 270; 9.65%) and male (n = 178; 6.36%) respectively. Regarding epidemiology, drugs, especially anxiolytics, with digestive tract and evolution to cure were the characteristics most present in the notifications. Conclusion: Suicide attempts and abuse were the circumstances for their reports and the most recurrent ones, with drugs, especially anxiolytics and antidepressants, in the digestive tract being the most used. In the cases evaluated, the outcome of the cure without sequel predominated.