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This article describes PypeR, a Python package which allows the R language to be called in Python using the pipe communication method. By running R through pipe, the Python program gains flexibility in sub-process controls, memory control, and portability across popular operating system platforms, including Windows, GNU Linux and Mac OS X. PypeR can be downloaded at http://rinpy.sourceforge.net/.doi:10.18637/jss.v035.c02 fatcat:gbpjp4icy5h5ndzryqt77lvrk4