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Background We assessed visual residual tumour cells (VRTC) with both Becker's tumour regression grading (TRG) system and Japanese TRG system in esophageal squamous cell carcinoma (ESCC) patients treated with neoadjuvant therapy followed by surgery. Methods We compared Becker system and Japanese system in 175 ESCC patients treated between 2009 and 2015. Results According to Becker system, the 5-year DFS/DSS rates were 70.0%/89.3, 53.8%/56.7, 43.0%/49.0, and 42.4%/39.1% for TRG 1a (VRTC 0), TRGdoi:10.1186/s12885-020-07779-0 pmid:33535987 fatcat:tf6v2jul65fdvjic7jxxabrdoi