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Despite the important role of Metalloproteinase (MMP) in β-cellular matrix remodeling there is clearly not enough data concerning the MMP proteolytic activity during first three weeks (early scar changes) of postoperative gastric ulcers. Thus the main aim of our work was the MMP, TIMP-1 and bFGF overall activity determination as well as their role in post-burn wound healing in case of the 2 nd degree esophagus acid burn infliction. The greatest increase in the metalloproteinase activity anddoi:10.4066/biomedicalresearch.29-18-394 fatcat:sp2wfixnnvchliit4vwklxfqsy