One-pot preparation of carbamoyl benzotriazoles and their applications in the preparation of ureas, hydrazinecarboxamides and carbamic esters

Hui Mao, Huili Liu, Yawei Tu, Zhiyun Zhong, Xin Lv, Xiaoxia Wang
2016 Journal of the Serbian Chemical Society  
Carbamoyl benzotriazoles were conveniently synthesized in one-pot from carboxylic acids, diphenyl phosphorazidate (DPPA) and 1H-benzotriazole (BtH). The reactivity and applications of carbamoyl benzotriazoles were also explored. Carbamoyl benzotriazoles react smoothly with amino acids, hydrazines and alcohols, thus providing facile access to the corresponding ureas, hydrazinecarboxamides and carbamic esters, respectively, in good to excellent yields.
doi:10.2298/jsc150126069m fatcat:mb4xdtjblvcqnljj4ek3nn53tm