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Whole-genome phylogenetic studies require various sources of phylogenetic signals to produce an accurate picture of the evolutionary history of a group of genomes. In particular, sequence-based reconstruction will play an important role, especially in resolving more recent events. But using sequences at the level of whole genomes means working with very large amounts of data-large numbers of sequences-as well as large phylogenetic distances, so that reconstruction methods must be both fast anddoi:10.1142/9789812799623_0020 fatcat:7feoggxspjhy7jthfez2jnpsra