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Role of poly(ADP-ribose)polymerase 2 in DNA repair
Biopolymers and Cell
Branch of the Russian Academy of Sciences 8, Akademika Lavrentieva Ave., Novosibirsk, Russian Federation, 630090 firstname.lastname@example.org Poly(ADP-ribosyl)ation is a posttranslational protein modification significant for the genomic stability and cell survival in response to DNA damage. Poly(ADP-ribosyl)ation is catalyzed by poly(ADP-ribose)polymerases (PARPs), which use NAD + as a substrate, synthesize polymer of (ADP)-ribose (PAR) covalently attached to nuclear proteins including PARPdoi:10.7124/bc.00004d fatcat:ogyypq256jds5nptu56mokbd3i