Pancreatic Stone Protein: Review of a New Biomarker in Sepsis

Pedro Fidalgo, David Nora, Luis Coelho, Pedro Povoa
2022 Journal of Clinical Medicine  
Sepsis is a life-threatening syndrome characterized by a dysregulated host response to an infection that may evolve rapidly into septic shock and multiple organ failure. Management of sepsis relies on the early recognition and diagnosis of infection and the providing of adequate and prompt antibiotic therapy and organ support. A novel protein biomarker, the pancreatic stone protein (PSP), has recently been studied as a biomarker of sepsis and the available evidence suggests that it has a higher
more » ... diagnostic performance for the identification of infection than the most used available biomarkers and adds prognostic value. This review summarizes the clinical evidence available for PSP in the diagnosis and prognosis of sepsis.
doi:10.3390/jcm11041085 pmid:35207355 pmcid:PMC8880320 fatcat:62yboebzcfcnta5fhkheuhsnhy