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Label-Free, Longitudinal Visualization of PDT ResponseIn Vitrowith Optical Coherence Tomography
2012
Israel Journal of Chemistry
A major challenge in creating and optimizing therapeutics in the fight against cancer is visualizing and understanding the microscale spatiotemporal treatment response dynamics that occur in patients. This is especially true for photodynamic therapy (PDT), where therapeutic optimization relies on understanding the interplay between factors such as photosensitizer localization and uptake, in addition to light dose and delivery rate. In vitro 3D culture systems that recapitulate many of the
doi:10.1002/ijch.201200009
pmid:23316088
pmcid:PMC3538822
fatcat:q3ibqjo3xrgghhzjmqcypjqmkm