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Elderly patients have medical and psychological problems affecting all major organ systems. These problems may alter the pharmacokinetics and/or pharmacodynamics of medications, or expose previous neurologic deficits simply as a result of sedation. Delayed arousal, therefore, may arise from structural problems that are pre-existent or new, or metabolic or functional disorders such as convulsive or nonconvulsive seizures. Determining the cause of delayed arousal may require clinical, chemical,doi:10.1016/j.anclin.2009.07.007 pmid:19825485 pmcid:PMC3036001 fatcat:sy6xhmvx4fazbk5lapq2bukpg4