Effect of resistance training combined with aerobic exercise on aortic arterial stiffness in older adults: a secondary analysis of randomized controlled trial

Keisei Kosaki, Yosuke Osuka, Kiyoji Tanaka, Seiji Maeda
2019 The Journal of Physical Fitness and Sports Medicine  
Aerobic exercise prior to resistance training is likely to have a preventive effect on arterial stiffening caused by resistance training alone. The purpose of this study was to examine, as secondary analysis, the effect of aerobic exercise before resistance training on aortic arterial stiffness in older adults. A total of 56 participants were randomized to resistance training (RT) group (n = 28) or aerobic exercise (AE) + RT group (n = 28). All participants attended a supervised exercise
more » ... g program (RT or AE + RT) twice a week for 12 weeks and were given fortified milk. Arterial stiffness was evaluated by pulse wave velocity (PWV) between carotid and femoral regions (e.g., aorta) and between femoral and ankle regions (e.g., leg). There was no significant difference between the two groups at all baseline measurements. After the intervention, although there was no significant interaction, carotid-femoral PWV was significantly increased only in the RT group (1032 ± 35 vs. 1072 ± 33 cm/sec, P < 0.05). Femoralankle PWV was not significantly changed in either group. Our findings reveal that resistance training significantly increases aortic arterial stiffness (carotid-femoral PWV); however, aerobic exercise before resistance training attenuates the aortic arterial stiffening in older adults. These results suggest that aerobic exercise before resistance training is likely to prevent the unfavorable effects of resistance training on vascular health in older adults. Special Issue 204 JPFSM : Kosaki K, et al. Methods Study design and participants. This study was a prespecified sub-study (secondary analysis) of an open, randomized controlled trial between September and December 2015 (UMIN000018972) 13) . This interventional study protocol received approval from the Ethics Committee of the University of Tsukuba, Japan (Tai27-9: 07/01/2015). Participants were eligible for inclusion if they (1) were aged 65 to 79 years, (2) were not restricted from exercise by a physician, (3) did not habitually conduct moderate intensity aerobic or resistance training, (4) had not participated in another clinical trial within one year, (5) did not have hypolactasia or milk allergy, (6) did not use diabetic medications, and (7) agreed to participate in the present study. We excluded participants who (1) had severe heart disease, cerebrovascular disease, or renal dysfunction, (2) had a habit of drinking too much milk (more than 2 cups/day), (3) participated in walking or strength exercise at light intensity. Finally, a total of 56 older adults participated in this study as previously reported 13) . All the participants provided written informed consent, and this study complied with the Declaration of Helsinki.
doi:10.7600/jpfsm.8.203 fatcat:2g7wyfczffaipaoxg6vf3ezhna