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Synthesis, characterization and biological evaluations of 2-(4-hydroxyaryl)-N'-[{5'-(substituted aryl)-furan-2'-yl}-methylidene]-ketohydrazides Schiff bases
2014
Scholars Research Library Der Pharma Chemica
unpublished
Schiff bases. The structures of these compounds were elucidated by IR, 1 HNMR, Mass spectral data and CHN analysis. The title compounds 3a-k, have been evaluated in vitro antibacterial screening against Gram positive bacterial strains S. aureus, B. cereus , E. faecalis and S. epidermidis and Gram negative bacteria strains E. coli , S. typhi, S. dysenteriae and K. pneumoniae. The synthesized Schiff bases also showed significant anthelmintic activity against two species of earthworms (Pheritima posthuma and Perionyx excavates).
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