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Performing computation inside living cells offers life-changing applications, from improved medical diagnostics to better cancer therapy to intelligent drugs. Due to its bio-compatibility and ease of engineering, one promising approach for performing in-vivo computation is DNA strand displacement. This paper introduces computer architects to DNA strand displacement "circuits", discusses associated architectural challenges, and proposes a new organization that provides practical composability.doi:10.1145/2485922.2485938 dblp:conf/isca/MuscatSCS13 fatcat:kg3iqjd5znh43hb55geyj3dvhi