Intralesional Platelet-rich Plasma Therapy vs Intralesional Triamcinolone Acetonide for the Treatment of Alopecia Areata

Pooja Agrawal, Hemangi R Jerajani, Saurabh Jindal, Shibban K Kaul, Chander P Puri
2018 MGM Journal of Medical Sciences  
Alopecia areata (AA) is a common autoimmune condition causing hair loss. Platelet-rich plasma (PRP) has emerged as a new treatment modality in dermatology, and preliminary evidence has suggested that it might have a beneficial role in hair growth. Aims and objectives: To compare the efficacy of intralesional PRP therapy vs intralesional triamcinolone acetonide (TrA) for the treatment of AA in a randomized, single-blinded, placeboand active-controlled parallel study. Materials and methods:
more » ... and methods: Thirty AA patients were randomized into two groups to receive intralesional injections of PRP or TrA. Half the number of patches in each patient were treated and other half were injected with placebo (normal saline). A total of three treatments were given for each patient at one month intervals. The evaluation was done by severity of alopecia tool (SALT) scoring, dermoscopic evaluation of dystrophic hair, and patient satisfaction. Patients were followed up for 6 months. Observations and results: Intralesional TrA was found to give better results as compared with intralesional PRP. Conclusion: Intralesional TrA gives superior results in AA as compared with intralesional PRP.
doi:10.5005/jp-journals-10036-1187 fatcat:hdgwbdmzsff47mqd3nhyqi6qom