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Study on Chemical Profile and Neuroprotective Activity of Myrica rubra Leaf Extract
2017
Molecules
The chemical profile of Myrica rubra (a native species in China) leaf extract was investigated by UPLC-PDA-HRMS, and the neuroprotective activity of two characteristic constituents, myricanol and myricetrin, was evaluated with N2a cells using H 2 O 2 -inducedoxidative challenge through a series of methods, e.g., MTT assay, ROS assay and [Ca 2+ ]i assay. Among the 188 constituents detected in the extract of Myrica rubra leaf, 116 were identified definitely or tentatively by the comprehensive
doi:10.3390/molecules22071226
pmid:28737731
fatcat:gy6qpxiv25gltb4vwzngeeov4q