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Percutaneous biopsies have a good sensitivity and specificity for the diagnosis of bone lesions. Aim: To report the experience with 270 percutaneous bone lesions biopsies guided with fluoroscopy or computed tomography. Material and Methods: Retrospective review of the medical records of 270 patients (mean age 53.4 years, range 4 to 95 years; 134 female) subjected to a percutaneous biopsy of a bone lesion, guided either by computed tomography or fluoroscopy. The final analysis included the tumordoi:10.4067/s0034-98872006001000010 pmid:17186098 fatcat:27g3nmlprvdgbg47tvbwchpbxi