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Nickel: a unique allergen – from molecular structure to European legislation
2007
Expert Review of Clinical Immunology
Nickel is a unique, mysterious and troublesome chemical element. Its molecular structure (unfilled electron shell) determines the high-reactivity and multidirectional biological effects. Some authors classify nickel as trace element, although its biological role in animal and human metabolism remains unclear. Conversely, nickel possesses strong sensitizing potential: as many as 65 million Europeans may be allergic to nickel. In this article, we review chemical and biological properties of
doi:10.1586/1744666x.3.6.851
pmid:20477134
fatcat:lvlceuimnfga3eotgn5y2vhkju