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Patients with chronic lymphocytic leukemia (CLL) harboring TP53 aberrations (TP53abs; chromosome 17p deletion and/or TP53 mutation) exhibit an unfavorable clinical outcome. Chromosome 8 abnormalities, namely losses of 8p (8p−) and gains of 8q (8q+) have been suggested to aggravate the outcome of patients with TP53abs. Research Paper Oncotarget 80917 www.impactjournals.com/oncotarget However, the reported series were small, thus hindering definitive conclusions. To gain insight into this issue,doi:10.18632/oncotarget.13106 pmid:27821812 pmcid:PMC5348364 fatcat:wszsyonmyjdfvh2iqgrf6d2xmm