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Radiation-induced angiosarcoma of the breast (RIAB) is an exceedingly rare secondary malignancy arising from prior radiation therapy. They are both difficult to diagnose and treat and are noted to have high rates of local recurrences. We present a case of a 59-year-old female who presented with RIAB 5 years after undergoing breast-conserving therapy for invasive ductal carcinoma.doi:10.33309/2639-9164.010103 fatcat:uocfrejesvezdie6mxmi6feela