OVOL2 Maintains the Transcriptional Program of Human Corneal Epithelium by Suppressing Epithelial-to-Mesenchymal Transition

Koji Kitazawa, Takafusa Hikichi, Takahiro Nakamura, Kanae Mitsunaga, Azusa Tanaka, Masahiro Nakamura, Tatsuya Yamakawa, Shiori Furukawa, Mieko Takasaka, Naoki Goshima, Akira Watanabe, Keisuke Okita (+4 others)
2016 Cell Reports  
Graphical Abstract Highlights d Identification of a transcription factor that can functionally maintain human CECs d OVOL2 can activate CEC-specific genes in heterologous cell types d OVOL2 represses mesenchymal genes in CECs d EMT may regulate transcriptional programs of surface and neuroectoderm
doi:10.1016/j.celrep.2016.04.020 pmid:27134177 fatcat:xceoj7mmunfhjhcdncjvako5yu