Comparison Between Adult Endocarditis Due to β-Hemolytic Streptococci (Serogroups A, B, C, and G) and Streptococcus milleriA Multicenter Study in France

Agnès Lefort
2002 Archives of Internal Medicine  
for the β-Hemolytic Streptococci Infective Endocarditis Study Group Background: Limited data exist on infective endocarditis (IE) due to Streptococcus milleri (Sm) or ␤-hemolytic streptococci (BHS). Because BHS and Sm share some physiologic and pathogenic properties, we wondered whether IE caused by these streptococci might present similarities. Methods: Through a nationwide retrospective study in France, the medical and microbiologic charts of adults with definite Sm or BHS IE observed between
more » ... January 1, 1991, and December 31, 1996, in university and general hospitals were reviewed. Results: Fifty-six patients had BHS IE (33 men and 23 women; median age, 59 years; range, 18-91 years) and 29 had Sm IE (18 men and 11 women; median age, 66 years; range, 37-97 years). The BHS group tended to have more underlying medical conditions (46%) and fewer previous cardiopathies (48%) than the Sm group (28% and 71%, respectively). Multivariate analysis showed that a (REPRINTED) ARCH INTERN MED/ VOL 162, NOV 25, 2002 WWW.ARCHINTERNMED.COM 2450
doi:10.1001/archinte.162.21.2450 pmid:12437404 fatcat:kugd5tgkcjanbnyrhqrlanhnaa