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Bariatric surgery has been proved to be effective and sustainable in the long-term weight-loss and remission of metabolic disorders. However, the underlying mechanisms are still far from fully elucidated. After bariatric surgery, the gastrointestinal tract is manipulated, either anatomically or functionally, leading to changed bile acid metabolism. Accumulating evidence has shown that bile acids play a role in metabolic regulation as signaling molecules other than digestive juice. And most ofdoi:10.3389/fphys.2019.00374 pmid:31001146 pmcid:PMC6454391 fatcat:2rwsw6syyjhz3nymjjszwwq5ru