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GSMN-ML- a genome scale metabolic network reconstruction of the obligate human pathogen Mycobacterium leprae
2020
PLoS Neglected Tropical Diseases
Leprosy, caused by Mycobacterium leprae, has plagued humanity for thousands of years and continues to cause morbidity, disability and stigmatization in two to three million people today. Although effective treatment is available, the disease incidence has remained approximately constant for decades so new approaches, such as vaccine or new drugs, are urgently needed for control. Research is however hampered by the pathogen's obligate intracellular lifestyle and the fact that it has never been
doi:10.1371/journal.pntd.0007871
pmid:32628669
fatcat:ctlzvzzoabezpoxpcdgp2vlq7y