Breast Cancer Familial Risk [chapter]

Barbara Burwinkel, Yang Rongxi
2011 Encyclopedia of Cancer  
A B cell, or B lymphocyte, is one of the two major types of lymphocytes. The antigen receptor on B lymphocytes, usually called the B-cell receptor, is a cell-surface immunoglobulin. On activation by antigen, B cells differentiate into cells producing antibody molecules of the same antigen specificity as this receptor. B Cells play a major role in the body's response to foreign materials (viruses, bacteria, parasites, etc.) by generating antibodies to fight these intruders. ▶ Fluoxetine B
more » ... s Definition Constitutional symptoms consisting of fever >38 C, night sweats, and/or unintentional weight loss of >10% the body weight over a period of up to 6 months. B symptoms are relevant in non-Hodgkin lymphoma and Hodgkin lymphoma staging and are related to tumor burden and prognosis. ▶ Diffuse Large B-Cell Lymphoma ▶ Malignant Lymphoma, Hallmarks and Concepts B-raf-1
doi:10.1007/978-3-642-16483-5_6695 fatcat:7c34qkrcbvhstf4qm6sd3caxj4