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Relaxin and progesterone are myometrial inhibitors in the ovariectomized non-pregnant mini-pig
Intravenous bolus injections of pig relaxin which produced short-lived peaks of the hormone equivalent in concentration to those observed at term promptly rendered the uterus almost totally quiescent and the inhibition persisted for about 2\m=.\5h. During this time the uterus remained responsive to oxytocin. The main effect of relaxin was to reduce the frequency of intrauterine pressure cycles rather than the amplitude. In contrast progesterone, which also inhibited myometrial activity, tookdoi:10.1530/jrf.0.0760205 pmid:3944791 fatcat:nzxnum3r7zeytccuzpfdpogisi