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0.55 points, respectively; group difference, 0.89 points; 95%CI -3.89 to 5.68; p=0.713). Week 52 least squares means for body weight and KOOS pain showed similar results ( Figure 2 ). 4 patients in the intervention and 4 patients in the control groups experienced serious adverse events, and no deaths were observed. Conclusion: In overweight patients with knee OA, an 8-week low-calorie diet intervention significantly reduced body weight and knee pain. Liraglutide treatment added after thedoi:10.1136/annrheumdis-2019-eular.1329 fatcat:5u2ltt3xebejbbobyubpyde2oa