Herpes simplex virus type 2 seroprevalence, HIV and Antiretroviral therapy knowledge and beliefs in the general population in Kisumu, Kenya
Journal of AIDS and HIV Research
With the increasing use of antiretroviral therapy (ART) in developing countries, little is known on the potential impact of large-scale ART use on sexual behavior. We used Herpes simplex virus type 2 (HSV-2) infection as a marker for sexual behavior to aid in assessing the association between ART related knowledge and beliefs and sexual behavior. This cross-sectional study analyzed secondary data collected in Kisumu's general population. A total of 1,655 participants (749 men, 906 women) aged
... , 906 women) aged 15 to 49yrs were interviewed. Socio-demographic factors, prevalence of HSV-2 and ART related knowledge and beliefs and their association with HSV-2 infection were evaluated. Overall, the prevalence of HSV-2 was 53%, and significantly higher in females (65%) than males (38%), p<0.001. Males and females with only primary education, history of drug abuse, who have ever been married and of Luo ethnic community were more likely to have HSV-2 infection. Overall, 17% believed that ART cured HIV/AIDS. Males who believed ART cured HIV had significantly >2 times odds of having HSV-2 (aOR: 2.02, 95% CI: 1.1 to 3.43) similar observations in females (aOR: 2.14, 95% CI: 1.34 to 3.40). Misinformation on ART capability may lead to increased HIV and sexually transmitted infection incidence if people think they are a cure for HIV. Targeted informative messages on ART to those at risk may aid in reducing the incidence of HSV-2.