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Influence of a new virostatic compound on the induction of enzymes in rat liver
1975
Arzneimittel-Forschung
Preserved Fulltext
The virostatic compound N,N-diethyl-4-[2-(2-oxo-3-tetradecyl-1-imidazolidinyl)-ethyl]-1-piperazinecarboxamide-hydrochloride (5531) was analyzed as to its effect on the induction of tryptophan-pyrrolase and tyrosineaminotransferase in rat liver. 1. The basic activity of the enzymes was not influenced by the substance either in normal or in adrenalectomized animals. 2. The induction of the enzymes by cortisone increased in the presence of the compound whereas the substrate induction remained
pmid:24
fatcat:4ipwyutcjfb7xoexmlun7vsquy