A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is
The abortive infection K (AbiK) system of Lactococcus lactis is a powerful antiviral defense mechanism that acts in the period after phage DNA enters the cell but before new progeny are released. The N-terminal domain of AbiK encodes a novel DNA polymerase that in vitro uses an internal amino acid to synthesize an un-templated DNA. The C-terminal domain of AbiK, on the other hand, has not been biochemically characterized. In the first of two projects presented in this thesis, strategies weredoi:10.11575/prism/36599 fatcat:7v7fdstiqvfvhog53g3aj5mks4