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Decision letter: Evolution of cytokine production capacity in ancient and modern European populations
[peer_review]
2021
unpublished
As our ancestors migrated throughout different continents, natural selection increased the presence of alleles advantageous in the new environments. Heritable variations that alter the susceptibility to diseases vary with the historical period, the virulence of the infections, and their geographical spread. In this study we built polygenic scores for heritable traits that influence the genetic adaptation in the production of cytokines and immune-mediated disorders, including infectious,
doi:10.7554/elife.64971.sa1
fatcat:5bnx6eojmralrj42jtlnvoevuq