We have used the Spitzer Space Telescope in February 2016 to obtain high cadence, high signal-to-noise, 17-hour duration light curves of Neptune at 3.6 and 4.5 μm. The light curve duration was chosen to correspond to the rotation period of Neptune. Both light curves are slowly varying with time, with full amplitudes of 1.1 mag at 3.6 μm and 0.6 mag at 4.5 μm. We have also extracted sparsely sampled 18-hour light curves of Neptune at W1 (3.4 μm) and W2 (4.6 μm) from the WISE/NEOWISE archive at

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... x epochs in 2010-2015. These light curves all show similar shapes and amplitudes compared to the Spitzer light curves but with considerable variation from epoch to epoch. These amplitudes are much larger than those observed with Kepler/K2 in the visible (amplitude ∼0.02 mag) or at 845 nm with the Hubble Space Telescope in 2015 and at 763 nm in 2016 (amplitude ∼ 0.2 mag). We interpret the Spitzer and WISE light curves as arising entirely from reflected solar photons, from higher levels in Neptune's atmosphere than for K2. Methane gas is the dominant opacity source in Neptune's atmosphere, and methane absorption bands are present in the HST 763, and 845 nm, WISE W1, and Spitzer 3.6 μm filters.