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DO NSAID/COX-2 INHIBITORS INCREASE NONUNION AFTER FRACTURE SURGERY? DILEMMA AND CONSIDERATION IN USE
JOINTS (Journal Orthopaedi and Traumatology Surabaya)
Nonunion accounts for 2 to 10% of fracture complications. It diminishes the quality of life and increases the risk of mortality. Several circumstances, including smoking, metabolic disorders, dietary inadequacy, and nonsteroidal anti-inflammatory drugs (NSAIDs), may predict the development of nonunion. In order to treat postoperative pain, NSAIDs are frequently used, including orthopedic conditions, particularly in the pain management of fracture. Using NSAIDs/cyclooxygenase (COX)-2 inhibitorsdoi:10.20473/joints.v11i2.2022.70-77 fatcat:67khr352fvfqpgttwifkxqauye