T-Cells, Graft-Versus-Host Disease, and Graft-Versus-Leukemia [chapter]

Richard Champlin, Sergio Giralt, James Gajewski
1996 Molecular Biology of Hematopoiesis 5  
Coronary artery disease (CAD) distribution becomes more abundant in the developing world. Coronary Artery Bypass Graft (CABG) is one of the treatments. If there are three blocked coronary arteries, surgeons can use two methods to perform CABG: Conventional graft and T graft. Estimation and comparison of these two methods for LAD, CX & PDA is the aim of this study. First two bypass graft methods were modeled in NX software then simulated with ADINA software. Fluid Solid Interaction (FSI) was
more » ... idered for simulation with more realistic condition. Pulsatile pressure was used for simulation as well. As will be explained later, it is an appropriate boundary condition for stenosis properties. From the results, coronary arteries flow in T graft bypass is less than that in conventional graft by the factor of 0.2 to 0.5. Then T graft bypass does not provide sufficient flow for PDA. In addition, vortex and wall shear stress (WSS) show more possibility of T graft blockage. Although it is estimated from effective stress that failure in artery may be less in T graft bypass.
doi:10.1007/978-1-4613-0391-6_1 fatcat:rh7j7avv45cflmwlcklzmqt2pm