An 82-year-old woman who had experienced two episodes of amaurosis fugax in her left eye presented with vision loss. She was diagnosed with impending retinal vein occlusion (RVO) of the left eye and received an intravitreal injection of ranibizumab. One month after this injection she was diagnosed with ischemic RVO. At 8-weeks post-presentation, extremely ischemic features were observed of severe vascular attenuation and extensive retinal capillary obliteration. She experienced no visual improvement over the following several months.