Syntheses of 4-(1H)-Quinolones and the Brominated or Methoxy Substituted Derivatives

Menglin Ma, Jianbiao Huang, Yuliang Wang, Shuhua Chen, Hua Chen
2013 Youji huaxue  
A simple and new synthetic approach to 4-(1H)-quinolones was described. This method was started from ethyl 3,3-diethoxypropanoate and aniline via a synthetic sequence of preparation of key intermediate 3-(phenylimino)propionate and cyclization reaction. The brominated or methoxy substituted derivatives were synthesized by this new method as well.
doi:10.6023/cjoc201210031 fatcat:lskjj6yau5exrmljztg5dyzeae