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Initial evaluation of the Roche COBAS TaqMan HIV-1 v2.0 assay for determining viral load in HIV-infected individuals
2009
Antiviral Therapy
HIV type-1 (HIV-1) genetic diversity poses a challenge for the development of diagnostic tests based on nucleic acid amplification, which can be overcome, at least in part, by targeting multiple genomic regions. The new Roche Diagnostics COBAS TaqMan (CTM) HIV-1 v2.0 assay uses multiplex real-time PCR detection of sequences in the long terminal repeat and gag regions within the HIV-1 genome. Methods: We conducted initial comparative testing of HIV-1 viral load values in plasma samples from
doi:10.3851/imp1427
pmid:20032549
fatcat:pr33nfyh3bfejhl3s2gizbnlou