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An efficient method to produce recombinant bacterial effector Tir coupled cytoskeleton protein (TCCP) complexed with host protein insulin receptor tyrosine kinase substrate (IRTKS)
English
2013
African Journal of Microbiology Research
English
An important pathogenic process in enterohemorrhagic Escherichia coli (EHEC) associated diseases is the formation of attaching and effacing (A/E) lesions, which are a typical pathological change in host cells. The classical pathway for A/E lesion formation requires the participation of proteins from both bacteria and host cells, namely intimin, translocated intimin receptor (Tir), insulin receptor tyrosine kinase substrate (IRTKS), Tir coupled cytoskeleton protein (TCCP), ARP3/2, and N-WASP.
doi:10.5897/ajmr2013.5463
fatcat:lt2k4xbx5reylpjyeseyjtg5tu