Changes in Cardiorespiratory Parameters during the Management of status Epilepticus in Children: A Prospective Randomized Controlled Study

Mudasir Nazir, Sheeraz A. Dar, Wasim A. Wani
2019 International Journal of Contemporary Medical Research [IJCMR]  
Status epilepticus is a common pediatric neurological emergency. Study aimed to compare changes in hemodynamic parameters during the management of pediatric status epilepticus using different first line anticonvulsants. Material and Methods: This prospective, randomized, study was done on Pediatric patients in the age group of 2 months to 16 years who present actively convulsing to the emergency department of pediatrics. Results: The mean time to regain consciousness in phenytoin, levetiracetam
more » ... and valproate groups was 122.3(± 45.4) minutes, 120.8(±42.8) minutes and 75.0(±30.7) minutes (mean±S.D) respectively. There was no significant difference in the three groups in various vital parameters like heart rate, systolic blood pressure, spo 2 and respiratory rate recorded at regular intervals in the acute stage (p value > 0.05). Conclusion: All the three anticonvulsants studied are safe and efficacious, and there is no significant difference in the cardiorespiratory parameters of three groups, and the time to regain consciousness was less in valproate group in comparison to other groups.
doi:10.21276/ijcmr.2019.6.5.56 fatcat:bl6kltym6negbnrq7coihnmu3q