Study of ehrlichiosis in kennel dogs under treatment and prevention during seven months in Dakar (Senegal)

Bernard Davoust, Oleg Mediannikov, Jeanne Chene, Raphaël Massot, Raphaël Tine, Mamadou Diarra, Jean-Paul Demoncheaux, Pierre Scandola, Frédéric Beugnet, Luc Chabanne
2013 Comparative Immunology, Microbiology & Infectious Diseases  
In Dakar kennels where morbidity and mortality attributed to diseases transmitted by ticks were high, we conducted a field study to assess the prevalence of Ehrlichia canis, Anaplasma platys and Babesia spp. infections in two kennels (n = 34 dogs) and to study the impact of tick protection. The first day of the study, the E. canis PCR were positive in 18 dogs (53%). A. platys was found in one dog and all dogs were negative for Babesia spp. After one month of doxycycline treatment, the number of
more » ... PCR positive dogs decreased significantly to 2 (5.9%). During seven months, all dogs were treated monthly topically with a novel combination (Certifect ® , Merial) delivering at least 6.7 mg fipronil/kg body weight, 8.0 mg amitraz/kg and 6 mg (S)-methoprene/kg. The number of PCR positive dogs remained stable all over the seven months, with 4 dogs being positive at Day 90 and 2 at Day 210. The combination of treatment and monthly prevention had a significant effect in the two kennels. All dogs remained healthy, which was not the case in previous years.
doi:10.1016/j.cimid.2013.08.002 pmid:24018180 fatcat:7iuxwrrc3nc2vh4njhhl3mjf6i