Abstract

Carrie A. Kubiak, Jessica J. Hsu, Jessica I. Billig, Ji Qi, Jennifer B. Hamill, Hyungjin M. Kim, Edwin G. Wilkins, Theodore Kung
2018 Plastic and Reconstructive Surgery, Global Open  
BACKGROUND: The increasing trend of women with unilateral breast cancer to electively undergo contralateral prophylactic mastectomy (CPM) in addition to treatment of the index breast has been the source of much debate. This trend has been primarily patient-driven, with conflicting, objective evidence supporting CPM. Critics have cautioned against the rising rates of CPM, questioning its indications and the possibility of increased risk over unilateral treatment. As such, any information that
more » ... information that can help practitioners better guide their patients towards the most beneficial and risk-reducing options is critical. The authors set out to better frame the risks and benefits of CPM in the treatment of unilateral breast cancer by evaluating outcomes of a large, consecutive cohort of patients. 1.38 to 11.91). CONCLUSION: These results underscore the premise that women with unilateral breast cancer who elect to undergo CPM may have an oncologic benefit by identifying an occult neoplasm in patients who lack typical risk factors associated with bilateral disease, such as positive BRCA status. Moreover, the findings presented here also suggest CPM does not pose an increased risk of complications compared to unilateral treatment.
doi:10.1097/01.gox.0000547047.69041.27 fatcat:n2e2ardd55hnlpxsdxc5433ecq