Levosimendan for Pediatric Anomalous Left Coronary Artery From the Pulmonary Artery Undergoing Repair: A Single-Center Experience

Chunrong Wang, Junsong Gong, Sheng Shi, Jianhui Wang, Yuchen Gao, Sudena Wang, Yong G. Peng, Jing Song, Yuefu Wang
2018 Frontiers in Pediatrics  
Peritoneal dialysis occurred in eight patients (40%) in the levosimendan group and two patients (10%) in the non-levosimendan group (p = 0.028). No significant difference was revealed in all-cause mortality within 180 days, which occurred in two patients (10%) in the levosimendan group and one (5%) in the non-levosimendan group (p = 1.00). Conclusion: Levosimendan's unique pharmacological properties have strong potential for cardiac function recovery among pediatric patients with ALCAPA with
more » ... with ALCAPA with impaired left ventricular function who have undergone surgical repair.However, any improvement from levosimendan on postoperative outcomes or mortality was not substantiated by this study and must be investigated further. Keywords: levosimendan, pediatric anomalous origin of the left coronary artery from the pulmonary artery, coronary artery reimplantation, left ventricular dysfunction, postoperative outcomes
doi:10.3389/fped.2018.00225 pmid:30155453 fatcat:34mlnrn5ofby3a5vyspp5t6jfu