The study evaluated the heamatological and serum biochemical indices of red sokoto goats fed different forms of neem (Azadirachta indica) leaves and a concentrate diet. The experiment was carried out at the small ruminants unit Teaching and Research Farm, Federal University of Kashere. Gombe state , Nigeria. Sixteen red sokoto goats (bucks) were allotted into four (4) treatments of four goats each. The goats were fed fresh neem leaves, neem leaves hay, neem leaves meal and neem leaves silage at

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... 300g/goat/day for treatments 1, 2, 3 and 4 respectively; and concentrate diet at 125g/goat/day for a duration of sixty three (63) days. Water was served ad-libitum. The experimental design was a completely randomized design; data were analyzed using a one way analysis of variance. The significant means were separated using least significant difference contained in SAS 2010 statistical package. The concentrate and the neem leaves were analyzed for their proximate composition using the method of AOAC 2000. Values for all the haematological indices except esinophil were not significantly different, the values for esinophil ranged from 1.07–1.57%. All the serum biochemical values were significantly (P<0.05) different, the values for urea ranged from 7.37 – 10.23mmol/l. It was concluded that the various forms of the neem leaves and the concentrate diet were safe for the goats. Further research using other breeds and other species of ruminants was recommended.