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A dual optical and nuclear imaging reagent for peptide labelling via disulfide bridging
Organic and biomolecular chemistry
We report a concise approach to a multimodal imaging reagent for peptide labelling via disulfide bridging. The reagent is constructed using a one pot, three component, [3 + 2] cycloaddition of a fluorescent azide with a dithiomaleimide-alkyne, with concomitant incorporation of 125I.doi:10.1039/c5ob01468a pmid:26299430 fatcat:flql4w5voze7hbanylaof37j6a