A prospective randomized, controlled study comparing low pressure versus standard pressure CO2 pneumoperitoneum during laparoscopic cholecystectomy

Mohd. Abass, Amarjeet Singh, Manish Sharma, Suleman Chaudhary
2022 International Journal of Surgery Science  
A prospective randomized controlled study was conducted to evaluate the feasibility and safety of low pressure co2 pneumoperitoneum versus standard pressure co2 pneumoperitoneum during laparoscopic cholecystectomy after receiving approval from ethical committee. Patients undergoing laparoscopic cholecystectomy were enrolled in the study after fulfilling eligibility criteria. According to surgical approach patients were randomly divided into two groups of 50 patients each, group A and group B
more » ... pectively. Group a Patients underwent laparoscopic cholecystectomy with low pressure co2 pneumoperitoneum [less than 8 mmHg] while group B patients underwent laparoscopic cholecystectomy under standard pressure co2 pneumoperitoneum [12 to 15 mmHg]. The following parameters were assessed primarily in terms of incidence of pain in post-operative period, changes in cardiorespiratory, changes in the organ system functions and length of the hospital stay. Results: Both groups were matched for the demographic parameters. We found that operative time was comparable in both groups whereas post-operative pain analgesic requirement, changes in cardiorespiratory, changes in organ system function and length of the hospital were flavouring low pressure co2 pneumoperitoneum in a statistically significant manner. (p< 0.01). Conclusion: Low pressure co2 pneumoperitoneum is ideal for laparoscopic cholecystectomy in terms of post-operative pain, use of analgesics, and length of hospitals stay and minimizes the adverse hemodynamic effect of co2 insufflation.
doi:10.33545/surgery.2022.v6.i2a.884 fatcat:oc3q3pwjhzetvnp46oooj6hssy