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Localization of the feline sarcoma virus fgr gene product (P70gag-actin-fgr): association with the plasma membrane and detergent-insoluble matrix
Journal of Virology
The v-fgr oncogene codes for a unique transforming protein (P709ag-ac"n-fgr) that contains virus-specific determinants and cell-derived sequences for both a tyrosine-specific kinase domain and an actin domain. We examined the subcellular distribution of the v-fgr protein by immunofluorescence microscopy and various cell fractionation techniques. By immunofluorescence, the v-fgr protein was localized in a diffuse cytoplasmic pattern within transformed cells. The v-fgr protein was not detectabledoi:10.1128/jvi.59.1.66-72.1986 fatcat:zqbvjmdwizbarab6vfeap4rggq