Neocortical Temporal Lobe Epilepsy

Eduard Bercovici, Balagobal Santosh Kumar, Seyed M. Mirsattari
2012 Epilepsy Research and Treatment  
Complex partial seizures (CPSs) can present with various semiologies, while mesial temporal lobe epilepsy (mTLE) is a well-recognized cause of CPS, neocortical temporal lobe epilepsy (nTLE) albeit being less common is increasingly recognized as separate disease entity. Differentiating the two remains a challenge for epileptologists as many symptoms overlap due to reciprocal connections between the neocortical and the mesial temporal regions. Various studies have attempted to correctly localize
more » ... he seizure focus in nTLE as patients with this disorder may benefit from surgery. While earlier work predicted poor outcomes in this population, recent work challenges those ideas yielding good outcomes in part due to better localization using improved anatomical and functional techniques. This paper provides a comprehensive review of the diagnostic workup, particularly the application of recent advances in electroencephalography and functional brain imaging, in neocortical temporal lobe epilepsy.
doi:10.1155/2012/103160 pmid:22953057 pmcid:PMC3420667 fatcat:oxuuex2m4jgp7llk5mmuzwuc3m