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Integrating ChIP-seq with other functional genomics data
2018
Briefings in Functional Genomics
Transcription is regulated by transcription factor (TF) binding at promoters and distal regulatory elements and histone modifications that control the accessibility of these elements. Chromatin immunoprecipitation followed by sequencing (ChIP-seq) has become the standard assay for identifying genome-wide protein-DNA interactions in vitro and in vivo. As large-scale ChIP-seq data sets have been collected for different TFs and histone modifications, their potential to predict gene expression can
doi:10.1093/bfgp/ely002
pmid:29579165
pmcid:PMC5888983
fatcat:zbfaimtxrvdyvmigeepu5o4cuq